We're building a talent pool of Biology professionals with Python proficiency to contribute to project-based AI development initiatives, focused on evaluating and enhancing frontier AI models.

Designed for biology specialists who enjoy deep technical problem-solving, this pipeline role is for those looking to apply their computational expertise to evaluate and push the boundaries of frontier AI models, relying on domain-specific tools such as NEURON, Brian2, OpenSim, AMICI, or MNE-Python, with verifiable, code-graded answers run inside isolated Linux environments.

Key Responsibilities

• Identify an appropriate computational biology package and build problems whose solution genuinely hinges on that tool's core capabilities, whether biophysical models, ODE/PDE systems, biomechanical formulations, or sequence algorithms.
• Develop full Python solutions for each problem, providing all necessary input files, model definitions, and network configurations as required.
• Establish the correct numerical output and define how close the AI model needs to get, using tolerance values appropriate to the biological context.
• Run the problem against the AI model across multiple parallel attempts, analyzing where it succeeds or falls short, and adjusting difficulty until the pass rate falls between 10% and 30%.
• Tune channel kinetics, stimulation protocols, and solver tolerances iteratively, building an understanding of how the model navigates complex neuronal, biomechanical, and systems biology problems.
• Hand off completed tasks to a senior reviewer in your subfield and refine based on their feedback before final submission.

Core Requirements

• Academic background in Biology or a closely related field.
• At least 2 years of hands-on experience in biology research, applied work, or teaching.
• Solid Python skills, applied to writing and validating computational solutions.
• Capacity to build problems that cannot be solved without specialized computational biology software.
• Excellent written and verbal communication skills in English.
• Ability to work independently in a remote, fast-paced environment.

Nice-to-Have

• Working knowledge of one or more domain-specific computational biology tools, including but not limited to NEURON, Brian2, NEST, OpenSim, AMICI, libroadrunner, MNE-Python, or Biopython, or a demonstrated ability to get up to speed independently.
• Prior exposure to how frontier AI models approach complex simulation tasks.
• Knowledge spanning more than one biology domain, such as computational neuroscience, biomechanics, or systems biology.
• Familiarity with containerized or sandboxed Linux execution environments.

The icing on the Kake:

💵 Competitive Pay in USD – Work globally, get paid globally.

🏡 Fully Remote – Simply put, we trust you.

🌱 Better Me Fund – We invest in your personal growth and passions.

❤️ Compassion is Badass – Join a community that invests in social good.

Please Note: Due to the high volume of applications, only shortlisted candidates will be contacted.

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